Preliminary programme
Please, note that the Conference agenda may still undergo minor changes due to organizational reasons.
SATELLITE SYMPOSIUM
09:00-10:00
Sponsored by Sobi
PROGRAMME
HAEMOPHILIA – RESEARCH
Chairs: Sébastien Lacroix-Desmazes (France), Ezio Zanon (Italy)
10:00-10:20
Engineering the factor VIII gene for enhanced functional activity
Lindsey George (USA)
10:20-10:40
Factor IX and the Padua mutation: what can we learn from this discovery
Paolo Simioni (Italy)
10:40-11:00
Laboratory assessment of non-replacement therapies
Armando Tripodi (Italy)
11:00-11:15
Discussion
11:15-11:45
Coffee break
ORAL COMMUNICATIONS
Chairs: Raimondo De Cristofaro (Italy), Pier Mannuccio Mannucci (Italy)
11:45-11:55
Immune cell pathways in protein and gene therapy efficacy in hemophilia
Giulia Mencarelli (Italy)
11:55-12:05
Investigating the novel role of factor VIII as a regulator of angiogenesis and promoter of endothelial barrier stability
Cristina Olgasi (Italy)
12:05-12:15
Immunogenicity of IdeS: the challenge of repeated use for clinical applications
Amélia Trecco (France)
12:15-12:25
Changes in ADAMTS13 conformation and related parameters in immune-mediated thrombotic thrombocytopenic purpura patients before an ADAMTS13 relapse
Andreea-Adela Icleanu (Hungary)
12:25-12:35
Histidine residues in the von Willebrand factor D4 assembly alter VWF function in response to shear stress
Tom McKinnon (UK)
12:35-12:45
Heparin proteoglycan mimetic APAC inhibits both von Willebrand factor and thrombin
Riitta Lassila (Finland)
KEYNOTE LECTURE
12:45-13:05
Economic implications of current and novel therapies in haemophilia
Brian O’Mahony (Ireland)
13:05-13:15
Discussion
13:15-13:25
Award ceremony
13:25-13:30
Closing remarks
Flora Peyvandi (Italy), Pier Mannuccio Mannucci (Italy)